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Uterine adenosarcoma arising from a subserosal adenomyoma: A case report
Shazia Fakhar1, Tehreem Zahid2, Yamina Ishtiaq3
1Professor of Gynaecology and Obstetrics, Shifa International Hospital, Sector H-8/4, Islamabad, Pakistan.
Gynecologic Oncology Reports
|March 14, 2022
Summary
Uterine adenosarcoma is a rare cancer, typically affecting post-menopausal women. This case highlights a 37-year-old presenting with symptoms initially thought to be fibroids, underscoring the importance of considering malignancy in younger patients.
Area of Science:
- Gynecologic Oncology
- Surgical Pathology
Background:
- Adenosarcoma is a rare malignant tumor arising from the uterus and cervix.
- These tumors predominantly affect post-menopausal women, making pre-menopausal presentation unusual.
Observation:
- A 37-year-old nulliparous woman presented with lower abdominal pain and backache.
- Initial diagnosis suggested multiple uterine leiomyomata, leading to a planned myomectomy.
- Intraoperative findings prompted suspicion of malignancy, necessitating a change in surgical management.
Findings:
- The patient underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy.
- Histopathological examination confirmed the diagnosis of adenosarcoma.
Implications:
- This case underscores the importance of considering rare malignancies, such as uterine adenosarcoma, even in pre-menopausal women presenting with symptoms mimicking benign conditions.
- Accurate intraoperative assessment and definitive surgical management are crucial for optimal patient outcomes in suspected gynecologic malignancies.

