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Updated: Sep 30, 2025

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
Published on: September 13, 2024
Degenerative temporomandibular joint diseases and their relation with sleep and emotional disturbance
Adrian Ujin Yap1,2,3,4, Xian-Han Zhang1,5, Ye Cao1,5
1Center for TMD & Orofacial Pain, Peking University, Hospital & School of Stomatology, Beijing, BJ, China.
Objective:
The relation of degenerative temporomandibular joint (TMJ) diseases (DJDs) with sleep and emotional disturbance were investigated.
Methods:
CBCT examination of patients (n = 358) with DC/TMD-defined intra-articular temporomandibular disorders was performed and stratified into NN: no DJD and no arthralgia; NA: no DJD with arthralgia; TO: osteoarthrosis; and TR: osteoarthritis. Sleep and emotional disturbance were assessed with the Pittsburgh Sleep Quality Index (PSQI) and Depression Anxiety Stress Scale-21 (DASS-21). Data were evaluated using non-parametric and multivariate logistic regression analyses (α = 0.05).
Results:
Distributions of NN, NA, TO, and TR groups were 23.2%, 27.1%,19.0%, and 30.7%, respectively. No significant differences in total-PSQI/DASS scores were detected among the four groups. The presence of pain and stress predicted poor quality sleep with odds ratios of 10.75 and 1.07, accordingly.
Conclusion:
Sleep quality was affected more by arthralgia and stress than the presence of TMJ DJDs.
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