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Complete Genome Sequence of Stenotrophomonas maltophilia Siphophage Suso

Qori Emilia1, Kyra Groover2, James Clark3,2

  • 1Department of Biology, Texas A&M University, College Station, Texas, USA.

Microbiology Resource Announcements
|March 14, 2022
PubMed

Insights

Phage Suso, a Stenotrophomonas maltophilia virus, has a 44,659-bp genome. It shows high genetic similarity to Stenotrophomonas phage SM171 and shares proteins with Beetravirus genus phages.

Area of Science:

  • Virology
  • Bacteriology
  • Genomics

Background:

  • Stenotrophomonas maltophilia is an opportunistic pathogen.
  • Bacteriophages (phages) are viruses that infect bacteria and can be used in phage therapy.
  • Understanding phage-bacterial interactions is crucial for controlling infections.

Purpose of the Study:

  • To characterize the genome and phylogenetic relationships of Stenotrophomonas maltophilia phage Suso.
  • To identify potential therapeutic applications of phage Suso.

Main Methods:

  • Genome sequencing of phage Suso.
  • BLASTn analysis for nucleotide identity comparison.
  • BLASTp analysis for protein homology comparison.

Main Results:

  • Phage Suso is a temperate siphophage with a 44,659-bp genome.
  • It shares 92% nucleotide identity with Stenotrophomonas phage SM171.
  • Phage Suso shares 14 proteins with Pseudomonas phages from the Beetravirus genus.

Conclusions:

  • Phage Suso represents a novel phage isolate of Stenotrophomonas maltophilia.
  • Its genetic relatedness suggests potential for phage-based interventions against S. maltophilia infections.
  • Further studies are warranted to explore the full potential of phage Suso in combating bacterial infections.

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