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The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus

Umut Gazi1, Ayşe Arıkan Sarıoğlu, Emrah Ruh1

  • 1Department of Medical Microbiology and Clinical Microbiology, Near East University, Nicosia, Cyprus.

The Turkish Journal of Pediatrics
|March 14, 2022
PubMed

Insights

Asymptomatic pediatric spread of coronavirus disease 2019 (COVID-19) is low, with only 1.3% of tested children showing infection. This finding suggests targeted serologic testing in schools to monitor SARS-CoV-2 in children.

Area of Science:

  • Pediatric infectious diseases
  • Epidemiology
  • Immunology

Background:

  • Initial assumptions suggested children significantly contributed to COVID-19 transmission.
  • Recent research indicates a lower role for children in SARS-CoV-2 spread.
  • The impact of asymptomatic pediatric infections requires further investigation.

Purpose of the Study:

  • To determine the prevalence of asymptomatic coronavirus disease 2019 (COVID-19) infections in children.
  • To assess the rate of asymptomatic pediatric SARS-CoV-2 seropositivity in Northern Cyprus.

Main Methods:

  • Retrospective analysis of 80 pediatric patients admitted to a university hospital between September 2020 and January 2021.
  • Patients selected had no COVID-19 symptoms or prior infection history.
  • Serum samples were analyzed using Dia.Pro SARS-CoV-2 IgG ELISA assays.

Main Results:

  • The study included 80 pediatric patients (40 male, 40 female) with an average age of 7.6 years.
  • One out of 80 patients (1.3%) tested positive for SARS-CoV-2 IgG antibodies.
  • This indicates a low rate of asymptomatic seropositivity in the studied pediatric cohort.

Conclusions:

  • The low asymptomatic seropositivity rate in children suggests a limited role in widespread transmission.
  • Implementing random serologic testing in schools can aid in monitoring pediatric SARS-CoV-2 infections.
  • Such monitoring strategies can contribute to public health efforts against COVID-19.
Abstract

Keywords:
IgGSARS-CoV-2childrenserologyseropositivity

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