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Gender differences in the association between environment and psychosis
Aysegul Yay Pence1, Lotta-Katrin Pries2, Maria Ferrara3
1Department of Psychiatry, Gazi University Hospital, Ankara, Turkey.
Schizophrenia Research
|March 14, 2022
Summary
Gender influences psychosis risk from environmental factors. Childhood adversity impacts women more, while urbanicity and migration affect men. Substance use links to psychosis risk differently across genders.
Area of Science:
- Neuroscience
- Psychiatry
- Environmental Health
Background:
- Psychosis spectrum disorder is linked to environmental exposures.
- The influence of gender on these associations is understudied.
Purpose of the Study:
- To systematically review gender-related differences in environmental risk factors for psychosis.
- To investigate associations between psychosis and childhood adversity, substance use, urbanicity, migration, season of birth, and obstetric complications.
Main Methods:
- Systematic review of 47 research articles from the PubMed database.
- Analysis of gender-specific associations between environmental exposures and psychosis.
Main Results:
- Childhood abuse shows a stronger association with psychosis risk and earlier onset in women.
- Urbanicity and immigration are more strongly linked to psychosis risk in men.
- Substance use association with psychosis risk may be stronger in women, despite higher comorbidity in men.
Conclusions:
- Gender-related differences in environmental risk factors for psychosis may exist.
- Further research is needed due to methodological limitations and inconsistent results.
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