M-SiSSR: Regional Endocardial Function Using Multilabel Simultaneous Subdivision Surface Registration

Area of Science:

• Cardiology
• Medical Imaging
• Computational Anatomy

Background:

• Accurate quantification of regional cardiac function is crucial in cardiology.
• Existing methods like Coherent Point Drift (CPD) and Simultaneous Subdivision Surface Registration (SiSSR) lack chamber-specific registration, leading to potential mesh slippage and inaccurate functional measurements.

Purpose of the Study:

• To introduce Multilabel-SiSSR (M-SiSSR), a novel method for registering labeled cardiac meshes that accounts for different cardiac structures.
• To evaluate the performance of M-SiSSR compared to the label-agnostic SiSSR for improved cardiac function tracking.

Main Methods:

• Developed M-SiSSR, a registration technique that assigns each triangle of a cardiac mesh to a specific cardiac structure.
• Compared M-SiSSR against the original SiSSR in tracking the endocardial surface and mitral valve plane.

Main Results:

• M-SiSSR demonstrated both visual and quantitative improvements over the label-agnostic SiSSR.
• Enhanced accuracy was observed in tracking the mitral valve plane, a critical landmark for cardiac function.

Conclusions:

• M-SiSSR offers a significant advancement in cardiac mesh registration by incorporating anatomical labels.
• This method promises more precise regional cardiac function quantification by preventing mesh slippage across chamber interfaces.