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Pyoderma Gangrenosum with Splenic Abscess- A Rare Association
Aditi Bansal1, Ankur Singla2, Aminder Singh3
1Department of Dermatology, Venereology and Leprology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Indian Dermatology Online Journal
|March 15, 2022
Summary
Pyoderma gangrenosum, a rare skin condition, can rarely affect internal organs. This case highlights visceral involvement presenting as a splenic abscess in a pyoderma gangrenosum patient.
Area of Science:
- Dermatology
- Internal Medicine
- Pathology
Background:
- Pyoderma gangrenosum (PG) is a rare, chronic neutrophilic dermatosis with unknown cause.
- PG classically presents as a rapidly progressing, painful necrotic ulcer with violaceous margins.
- Associated systemic conditions include inflammatory bowel disease, hematological malignancies, and rheumatologic disorders in 50-70% of cases.
Observation:
- Visceral involvement in PG is uncommon.
- Systemic manifestations of neutrophilic dermatoses typically involve sterile neutrophilic infiltrates in organs other than the skin.
- This report details a 38-year-old female diagnosed with PG and concurrent splenic abscess.
Findings:
- The patient presented with pyoderma gangrenosum.
- Splenic abscess was identified as a manifestation of visceral involvement.
- This case underscores the rare possibility of internal organ compromise in PG.
Implications:
- This case expands the understanding of pyoderma gangrenosum's potential systemic manifestations.
- Highlights the importance of considering visceral involvement in patients with refractory or atypical PG presentations.
- Suggests a need for further investigation into the mechanisms of extranodal neutrophilic infiltration in PG.
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