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Updated: Sep 30, 2025

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
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Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model

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Global genomic instability caused by reduced expression of DNA polymerase ε in yeast

Ke Zhang1, Yang Sui2,3, Wu-Long Li2

  • 1Institute of Microbiology, College of Life Science, Zhejiang University, 310058 Hangzhou, China.

Proceedings of the National Academy of Sciences of the United States of America
|March 15, 2022
PubMed

Keywords:
DNA polymeraseDNA replication stressgenome instabilityloss of heterozygositymitotic recombination

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