Related Experiment Video
Updated: Sep 30, 2025
Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
Significance of Ki67 expression in endometriosis for infertility
Elvin Piriyev1, Mona Mariella Gertz2, Sven Schiermeier3
1University Witten-Herdecke, Department of Obstetrics and Gynecology, Academic Hospital Cologne Weyertal University of Cologne, Germany.
Objective:
The aim of the study was to show the significance of Ki67 expression in endometriosis for infertility.
Study Design:
It was a retrospective analysis. 670 cases were analyzed. In 484 cases, immunohistochemical proliferation analysis was performed to determine the expression of Ki67. The indicated percentages of Ki67 expression were divided into three groups. An expression below 10% is considered low, 10-30% intermediate, and over 30% is considered high.
Results:
There was a significant correlation between Ki67 expression and postoperative pregnancy onset: 66,7% of patients with high proliferation activity became pregnant within one year postoperatively, whereas the 38,7% of patients with moderate and only 17,3% of patients with low Ki67 expression became pregnant.
Conclusion:
In this work, high Ki67 expression was more frequent than low Ki67 expression in women with infertility than in patients without infertility. These results contribute to the importance of endometrial resection in the context of infertility treatment.
More Related Videos
08:29Author Spotlight: Multiplex Immunohistochemistry for Understanding Immune Regulation by Uterine NK Cells in Pregnancy
Published on: October 25, 2024
05:16Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
Related Concept Videos
02:07Oogenesis
01:28Infertility in Females
Endometriosis, a condition characterized by abnormal growth of...