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Electro-acupuncture for protracted amphetamine abstinence syndrome: study protocol for a pragmatic randomized
Huan Ren1, Yiwei Zeng1, Min Zhang1
1School of Acupuncture-Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, China.
Trials
|March 16, 2022
Summary
Electro-acupuncture shows promise for managing protracted amphetamine abstinence syndrome (PAAS), a key factor in relapse. This study investigates its effectiveness in real-world settings to guide clinical practice.
Area of Science:
- Neuroscience
- Integrative and Complementary Medicine
- Psychiatry
Background:
- Protracted amphetamine abstinence syndrome (PAAS) is a major cause of relapse in amphetamine-type drug users.
- The management of PAAS is often underestimated.
- Electro-acupuncture presents a potential safe and effective therapy for PAAS, but evidence is limited.
Purpose of the Study:
- To assess the effectiveness of electro-acupuncture in treating protracted amphetamine abstinence syndrome (PAAS).
- To provide evidence supporting clinical decisions for PAAS management.
- To establish a basis for future trials comparing acupuncture with other treatments.
Main Methods:
- A prospective, two-center, randomized, waitlist-controlled, open-label pragmatic trial.
- 300 patients with PAAS will be recruited and randomized (1:1) to electro-acupuncture or a waitlist group.
- Treatment involves electro-acupuncture twice weekly for 4 weeks, with primary outcome being change in ACSA and secondary outcomes including HAMD, VAS, HAMA, PSQI, MoCA, and SF-36 scores.
Main Results:
- This section is not available in the provided abstract.
Conclusions:
- This study aims to evaluate electro-acupuncture's efficacy for PAAS in real-world clinical settings.
- Findings will inform clinical practice and future research comparing acupuncture to other interventions.
