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Updated: Sep 30, 2025
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Published on: July 5, 2021
How I do it: endonasal transcribriform approach for resection of esthesioneuroblastoma
J Curran Henson1, Amarbir Gill2, Jeremiah Alt2
1College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Background:
Olfactory neuroblastoma, also known as esthesioneuroblastoma, accounts for only 3-6% of sinonasal malignancies but confers a 40% 5-year overall survival.
Method:
The authors describe techniques for the endonasal, minimally invasive resection of an esthesioneuroblastoma in a 69-year-old man who presented with headaches and anosmia and describe surgical nuances and their effect on adjuvant therapy planning.
Conclusion:
This approach, along with microsurgical techniques, helped increase tumor visualization, improved marginal resection, and reduced surgical risk, which may improve patient outcomes. Multilayered reconstruction with a synthetic dural substitute and creation of a nasoseptal flap were performed to reduce postoperative cerebrospinal fluid leak.
