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Urodynamically proven lower urinary tract dysfunction in children after COVID-19: A case series
Ismail Selvi1, Muhammet İrfan Dönmez1, Orhan Ziylan1
1Division of Pediatric Urology, Department of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Lower Urinary Tract Symptoms
|March 16, 2022
Summary
COVID-19 infection can lead to lower urinary tract dysfunction (LUTD) in children, including incomplete bladder emptying and urinary retention, even months after diagnosis. Clinicians should consider recent COVID-19 infection in pediatric patients presenting with sudden-onset LUTD.
Area of Science:
- Pediatric Urology
- Infectious Diseases
- Nephrology
Background:
- COVID-19 has been associated with various non-respiratory symptoms.
- Previous reports noted urinary issues in adult COVID-19 patients, but pathophysiology remains unclear.
- This study investigates lower urinary tract dysfunction (LUTD) in pediatric COVID-19 survivors.
Observation:
- Three adolescent patients (14-17 years) developed LUTD post-COVID-19.
- Symptoms, including urinary frequency and nocturia, appeared a median of 3 months after COVID-19 diagnosis.
- No prior bowel issues or neurological etiological factors were identified.
Findings:
- Urodynamic studies revealed incomplete bladder emptying and urinary retention.
- Patients exhibited increased bladder compliance and high post-micturition residual volumes.
- Pressure flow studies showed an acontractile or hypocontractile detrusor during voiding.
Implications:
- Sudden-onset LUTD in children may be linked to prior COVID-19 infection.
- Clinicians should consider COVID-19 as a potential cause of pediatric LUTD.
- Further research is needed to elucidate the neuro-urological mechanisms of post-COVID-19 LUTD.
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