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Updated: Sep 30, 2025

Live-Cell Förster Resonance Energy Transfer Imaging of Metabolically Regulated Akt Activation Dynamics in HepG2 Cells
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Live-Cell Förster Resonance Energy Transfer Imaging of Metabolically Regulated Akt Activation Dynamics in HepG2 Cells

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Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake

Song-Hua Hu1, Xia-Di He1, Ji Nie1

  • 1Obstetrics & Gynecology Hospital of Fudan University, Institutes of Metabolism and Integrative Biology, State Key Laboratory of Genetic Engineering, School of Life Sciences and Institutes of Biomedical Sciences, Shanghai 200438, P.R. China; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Shanghai Key Laboratory of Medical Epigenetics, and Children's Hospital of Fudan University, Shanghai 200438, P.R. China.

Cell Reports
|March 16, 2022
PubMed

Keywords:
Akt signalingDHA/EPAfatty acylation

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