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Updated: Sep 30, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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Mechanisms of MHC-I Downregulation and Role in Immunotherapy Response

Brandie C Taylor1, Justin M Balko1,2

  • 1Department of Medicine, Cancer Biology, Vanderbilt University, Nashville, TN, United States.

Frontiers in Immunology
|March 17, 2022
PubMed

Keywords:
antigen presentationcancer immunotherapyimmune checkpoint inhibitionimmunoncologymajor histocompatibility complex class-I

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