Related Experiment Video
Updated: Sep 30, 2025

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Pityriasis rubra pilaris after COVID-19 vaccination: causal relationship or coincidence?]
A C Bramhoff1, U Wesselmann1, S T Bender1
1Zentrum für Dermatologie, Allergologie und Dermatochirurgie, Helios Universitätsklinikum Wuppertal, Universität Witten/Herdecke, Heusnerstr. 40, 42283, Wuppertal, Deutschland.
Abstract:
Numerous cutaneous side effects associated with COVID-19 vaccines have been described since their clinical approval. These include, among others, injection site reactions, urticarial, maculopapular and pityriasiform rashes or temporary exacerbations of a pre-existing chronic inflammatory skin disease. Herein we report about three cases of pityriasis rubra pilaris that occurred for the first time in close temporal relationship with the administration of a COVID-19 vaccine.
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