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Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

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Published on: August 16, 2016

Ionically Active MXene Nanopore Actuators.

Mehrnaz Mojtabavi¹, Wan-Yu Tsai², Armin VahidMohammadi³

¹Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.

Small (Weinheim an Der Bergstrasse, Germany)

|March 17, 2022

Summary

This summary is machine-generated.

This study introduces a novel nanopore-actuator system using MXene films. This system demonstrates reversible membrane swelling and contraction, enabling new possibilities for nanoscale biosensing.

Keywords:

MXenes actuation intercalation membranes nanopores

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Area of Science:

Materials Science
Nanotechnology
Electrochemistry

Background:

Two-dimensional (2D) materials exhibit tunable properties via reversible cation intercalation.
MXenes, a class of 2D carbides and nitrides, show promise in sensing and energy storage due to their intercalation characteristics.

Purpose of the Study:

To develop a coupled nanopore-actuator system utilizing MXene films.
To investigate the mechanical response of MXene membranes to electrochemical stimuli for biosensing applications.

Main Methods:

Fabrication of an ultrathin, free-standing MXene film as a nanopore support membrane and actuator.
Application of an electric field to induce cation (de)intercalation within the MXene flakes.
Monitoring membrane swelling/contraction via ionic conductance changes through the nanopore.

Main Results:

Demonstration of reversible swelling and contraction of the MXene membrane in response to electric fields.
Correlation between cation intercalation/deintercalation and membrane mechanical actuation.
Successful monitoring of these changes through ionic conductance measurements.

Conclusions:

The developed MXene-based nanopore-actuator system offers a novel platform for nanoscale mechanical actuation.
This system provides a foundation for designing advanced single-molecule biosensing platforms.
The study highlights the potential of MXenes in integrated nanoelectromechanical systems.