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Pyoderma gangrenosum caused by secukinumab successfully treated with risankizumab: a case report and literature
Akihiro Orita1, Daichi Hoshina1, Kuninori Hirosaki2
1Department of Dermatology, Otaru General Hospital, Otaru, Hokkaido, Japan.
Abstract:
We report a case of pyoderma gangrenosum (PG) caused by secukinumab, which was successfully treated with risankizumab. We also reviewed reported cases of PG caused by interleukin (IL)-17 inhibitors. The clinical course of this case indicates that IL-23 may play an important role in the pathogenesis of PG and therefore IL-23-targeting therapies may be a treatment option for PG.
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