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Cemiplimab in advanced cutaneous squamous cell carcinoma: the UK experience from the Named Patient Scheme

A Challapalli1, S Watkins2, G Cogill3

  • 1University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, UK.

Journal of the European Academy of Dermatology and Venereology : JEADV
|March 17, 2022
PubMed
Abstract

No abstract available in PubMed .

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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