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Related Concept Videos

Elastin is Responsible for Tissue Elasticity01:12

Elastin is Responsible for Tissue Elasticity

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Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
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Elastic Strain Energy for Shearing Stresses01:20

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As discussed in previous lessons, strain energy in a material is the energy stored when it is elastically deformed, a concept crucial in materials science and mechanical engineering. This energy results from the internal work done against the cohesive forces within the material. When a material undergoes shearing stress and corresponding shearing strain, the strain energy density, which is the energy stored per unit volume, is calculated. Within the elastic limit, where the stress is...
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The quantity that describes the deformation of a body under stress is known as strain. Strain is given as a fractional change in either length, volume, or geometry under tensile, volume (also known as bulk), or shear stress, respectively, and is a dimensionless quantity. The strain experienced by a body under tensile or compressive stress is called tensile or compressive strain, respectively. In contrast, the strain experienced under bulk stress and shear stress is known as volume and shear...
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Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
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Elastic Strain Energy for Normal Stresses01:22

Elastic Strain Energy for Normal Stresses

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Strain energy quantifies the energy stored within a material due to deformation under loading conditions, a fundamental concept in materials science and engineering. The strain energy can be modeled when a material is subjected to axial loading with uniformly distributed stress. In this scenario, the stress experienced by the material is the internal force divided by the cross-sectional area, and the strain induced is directly proportional to this stress through the modulus of elasticity.
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Elasticity01:12

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Elasticity is the ability of an object to withstand the effects of distortion and to return to its original size and shape once the forces causing deformation are removed. When an elastic material deforms under the action of an external force, it experiences internal resistance to the deformation. However, if no external force is applied, it returns to its original state.
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Optical coherence elastography to evaluate depth-resolved elasticity of tissue.

Chenming Yang, Zhen Xiang, Zhongliang Li

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    This study introduces a novel optical coherence elastography method to measure skin elasticity at different depths. The technique accurately assesses layered tissue elasticity, aiding in diagnosing skin diseases.

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    Area of Science:

    • Biomedical Optics
    • Biomaterials Science
    • Medical Imaging

    Background:

    • Skin elasticity measurement is crucial for diagnosing skin diseases.
    • Accurate depth-resolved elasticity of superficial biological tissue is an important research area.
    • Existing methods may have limitations in assessing multilayered tissue elasticity.

    Purpose of the Study:

    • To develop and validate an optical coherence elastography (OCE) technique for depth-resolved elasticity measurement of multilayered biological tissues.
    • To combine surface acoustic waves and shear waves for comprehensive elastic property evaluation.
    • To assess the accuracy and potential clinical applicability of the proposed OCE method.

    Main Methods:

    • The proposed OCE technique utilizes high-frequency surface acoustic waves to determine the Young's modulus of the superficial layer.
    • Shear wave velocities are subsequently calculated for deeper layers to obtain their respective Young's moduli.
    • Bilayer phantom experiments were conducted to validate the method's accuracy.

    Main Results:

    • The technique successfully measured depth-resolved elasticity in layered tissue-mimicking phantoms.
    • The maximum error in elastic estimation for each layer in bilayer phantom experiments was 2.2%.
    • The results demonstrate high accuracy in evaluating the elasticity of multilayered tissues.

    Conclusions:

    • The developed optical coherence elastography method accurately evaluates depth-resolved elasticity in layered tissues.
    • This technique shows significant potential for expanding clinical applications in diagnosing skin diseases.
    • The combination of surface and shear waves offers a robust approach for multilayered tissue elasticity assessment.