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Updated: Sep 30, 2025

Quantitative Determination of De Novo Fatty Acid Synthesis in Brown Adipose Tissue Using Deuterium Oxide
Published on: May 12, 2023
[Research Progress of Fatty Acid Desaturase 2 Gene in Glycolipid Metabolism]
Guo-Jie Wang1, Ye Tian1, Hui-Ying Zhang1
1Department of Obstetrics and Gynecology,Tianjin Medical University General Hospital,Tianjin 300052,China.
Abstract:
The fatty acid desaturase 2 (FADS2) gene encodes delta-6 desaturase (D6D) and is a member of the fatty acid desaturase gene family.D6D is the key enzyme catalyzing the transformation of linoleic acid and α-linolenic acid to long-chain polyunsaturated fatty acid (LC-PUFA).LC-PUFA play a crucial role in regulating the glycolipid metabolism of living organisms.In recent years,the activity of D6D and the single nucleotide polymorphism (SNP) of FADS2 gene have become a hot topic in the research on glycolipid metabolism.This article reviews the role of FADS2 gene in glycolipid metabolism.
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