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Related Experiment Video

Updated: Sep 30, 2025

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
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[Penetrating keratoplasty].

W Boucenna1, J-L Bourges2

  • 1Service d'ophtalmologie, université de Picardie Jules-Verne, CHU d'Amiens-Picardie, Amiens, France.

Journal Francais D'Ophtalmologie
|March 18, 2022
PubMed
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Penetrating keratoplasty, a corneal transplant, remains a valuable treatment for visual impairment. While newer lamellar grafts offer faster recovery, penetrating keratoplasty is still appropriate for specific indications with proper assessment and follow-up.

Area of Science:

  • Ophthalmology
  • Transplantation Surgery

Background:

  • Penetrating keratoplasty has been the gold standard for corneal diseases for over 100 years.
  • Visual impairment due to corneal disease is a significant global health concern.

Purpose of the Study:

  • To evaluate the continued relevance and appropriate indications for penetrating keratoplasty.
  • To compare penetrating keratoplasty with newer lamellar keratoplasty techniques.

Main Methods:

  • Review of historical and current surgical indications for penetrating keratoplasty.
  • Comparison of complication rates and functional rehabilitation between penetrating and lamellar keratoplasty.

Main Results:

  • Lamellar keratoplasty (anterior and endothelial) offers fewer complications and faster recovery.
Keywords:
Bullous keratopathyCorneal transplantGraft rejectionGraft survivalGreffe de cornéeInfectious keratitisKeratoconusKératites infectieusesKératocôneKératopathie bulleuseKératoplastie transfixiantePenetrating keratoplastyRejet de greffeSurvie du greffonTrephineTrépan

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  • Penetrating keratoplasty, though less frequent, remains indicated for specific corneal conditions.

    • Conclusions:

    • Proper patient selection and surgical technique are crucial for successful penetrating keratoplasty outcomes.
    • Penetrating keratoplasty, when indicated, provides good functional results with appropriate management.
    • Continuous follow-up is essential for optimizing refractive outcomes after penetrating keratoplasty.