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Related Concept Videos

Kidney Structure01:45

Kidney Structure

70.9K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
70.9K
Internal Anatomy of the Kidney01:12

Internal Anatomy of the Kidney

3.0K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
3.0K
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

1.8K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
1.8K

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Related Experiment Video

Updated: Sep 29, 2025

Nuclei Isolation from Adult Mouse Kidney for Single-Nucleus RNA-Sequencing
06:00

Nuclei Isolation from Adult Mouse Kidney for Single-Nucleus RNA-Sequencing

Published on: September 20, 2021

4.7K

Mapping the human kidney using single-cell genomics.

Felix Schreibing1,2, Rafael Kramann3,4,5

  • 1Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.

Nature Reviews. Nephrology
|March 18, 2022
PubMed
Summary
This summary is machine-generated.

Single-cell and spatial technologies reveal kidney cell types and interactions in development and disease. This research aids understanding of kidney disorders and potential new therapies.

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Last Updated: Sep 29, 2025

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Area of Science:

  • Single-cell genomics
  • Spatial transcriptomics
  • Kidney biology

Background:

  • Single-cell technologies offer deep insights into complex tissues.
  • The fetal kidney's development and cellular interactions are increasingly understood.
  • Adult kidney cell heterogeneity and disease mechanisms are being elucidated.

Purpose of the Study:

  • To detail cellular composition and interactions in kidney development.
  • To explore cell types in healthy adult kidneys and kidney diseases.
  • To identify therapeutic targets and biomarkers for kidney disorders.

Main Methods:

  • Single-cell genomics and sequencing
  • Spatial technology applications
  • Analysis of cellular heterogeneity and interactions

Main Results:

  • Characterization of fetal kidney development and adult kidney cell types.
  • Identification of cell types in acute kidney injury, glomerular diseases, and renal cell carcinoma.
  • Insights into myofibroblast origins and cell crosstalk in kidney fibrosis.

Conclusions:

  • Single-cell and spatial technologies are revolutionizing kidney research.
  • These technologies facilitate the discovery of biomarkers and therapeutic strategies for kidney diseases.
  • A comprehensive cellular map of the kidney is emerging, aiding understanding from development to disease.