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Updated: Sep 29, 2025

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Deep Vein Thrombosis is Common After Cardiac Ablation and Pre-Procedural D-Dimer Could Predict Risk.
Charo Bruce1, Karan Saraf2, Steven Rogers3
1Manchester Heart Centre, Manchester University NHS Foundation Trust, Manchester, UK.
Cardiac catheter ablation for supraventricular tachycardia (SVT) carries an 8.8% risk of deep vein thrombosis (DVT) in the catheterized leg. Prophylactic anticoagulation may be beneficial for patients undergoing this procedure.
Area of Science:
- Cardiology
- Vascular Medicine
- Interventional Cardiology
Background:
- Cardiac catheter ablation is a common treatment for supraventricular tachycardia (SVT).
- The procedure involves prolonged femoral vein cannulation, potentially increasing deep vein thrombosis (DVT) risk.
- ClinicalTrials.gov Identifier: NCT03877770.
Purpose of the Study:
- To determine the incidence of deep vein thrombosis (DVT) following cardiac catheter ablation for SVT.
- To identify risk factors associated with DVT development post-ablation.
Main Methods:
- Prospective, multi-center cohort study.
- Included patients undergoing ablation for atrioventricular nodal re-entry tachycardia or right-sided accessory atrioventricular connection.
- Excluded patients on anticoagulation/antiplatelet therapy; performed bilateral venous duplex ultrasonography post-procedure.
Main Results:
- Seven of 80 patients (8.8%) developed acute DVT in the intervention leg's femoral or iliac veins.
- No DVT was observed in the contralateral leg (p=0.023).
- Elevated pre-procedure D-dimer levels were significantly associated with DVT development (42.9% vs 4.1%, p=0.0081).
Conclusions:
- Cardiac catheter ablation without peri-procedural anticoagulation resulted in an 8.8% DVT rate in catheterized femoral or iliac veins.
- Peri-procedure prophylactic anticoagulation warrants consideration for SVT ablation patients.
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