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Updated: Sep 29, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Pharmacotherapies in eosinophilic esophagitis: state of the art
Elisa Marabotto1, Edoardo G Giannini2, Patrizia Zentilin2
1Gastrointestinal Unit, Department of Internal Medicine, University of Genoa, Genoa, Italy - elisa.marabotto@unige.it.
Abstract:
Eosinophilic esophagitis is a chronic immune-mediated esophageal disease with a Th2 inflammatory response to inhalant and food allergens that cause an eosinophilic infiltration of esophageal mucosa. The diagnosis requires an upper endoscopy with esophageal bioptic samples, in particular the number of eosinophils must be >15 eos/high power field. The main symptoms of EoE in adults are dysphagia and food impaction, and its incidence is growing. Nowadays, the etiology of EoE is not well understood and no standard therapy is available. Therefore, the aim of this review was to analyze the major studies present in literature regarding the various therapeutic approaches to this disease.
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