Initiation of protein synthesis in mammalian cells

Phosphorylation of eukaryotic initiation factor 4E (eIF4E) at Ser209 is not required for protein synthesis in vitro and in vivo.

European journal of biochemistry·2001

Proteasome inhibitors and immunosuppressive drugs promote the cleavage of eIF4GI and eIF4GII by caspase-8-independent mechanisms in Jurkat T cell lines.

FEBS letters·2001

Disruption of the interaction of mammalian protein synthesis eukaryotic initiation factor 4B with the poly(A)-binding protein by caspase- and viral protease-mediated cleavages.

The Journal of biological chemistry·2001

Differential requirements for caspase-8 activity in the mechanism of phosphorylation of eIF2alpha, cleavage of eIF4GI and signaling events associated with the inhibition of protein synthesis in apoptotic Jurkat T cells.

FEBS letters·2000

The role of 5'-leader length, secondary structure and PABP concentration on cap and poly(A) tail function during translation in Xenopus oocytes.

Nucleic acids research·2000

Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cells.

Cell death and differentiation·2000

The non-canonical CDK2 activator SPY1 uses separable mechanisms to activate phosphorylated and unphosphorylated CDK2.

The Biochemical journal·2026

Bisecting GlcNAc in N-glycan regulates synaptic maturation.

The Biochemical journal·2026

Loss of O-GlcNAc Transferase activity impairs the dynamic formation of protective stress granules in ischemic cardiomyocytes.

The Biochemical journal·2026

De novo flavonoid production in engineered Escherichia coli.

The Biochemical journal·2026

Atypical p38 kinase signaling and pathological impact on human health.

The Biochemical journal·2026

Solution Structures of Glycosaminoglycan-bound CXCL8 Complexes Determined by Small-Angle X-Ray Scattering (SAXS).

The Biochemical journal·2026

Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles.

Methods in molecular biology (Clifton, N.J.)·2026

Expression, Purification, and Structural Characterization of Membrane Proteins: A Case Study of the ABC Transporter MsbA.

Methods in molecular biology (Clifton, N.J.)·2026

A Dynamic Boolean Model of the Mammalian Cell Cycle: Enhanced Robustness and Mutational Analysis.

Methods in molecular biology (Clifton, N.J.)·2026

Electrical Properties in Biological Materials.

Chemical reviews·2026

Conformational Ensemble and Stabilization of Insulin by a Choline Ionic Liquid Elucidated through Markov State Models.

Journal of chemical information and modeling·2026

Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory.

Cell reports·2026

Related Experiment Videos

Initiation of protein synthesis in mammalian cells

Related Concept Videos

Phosphorylation of eukaryotic initiation factor 4E (eIF4E) at Ser209 is not required for protein synthesis in vitro and in vivo.

Proteasome inhibitors and immunosuppressive drugs promote the cleavage of eIF4GI and eIF4GII by caspase-8-independent mechanisms in Jurkat T cell lines.

Disruption of the interaction of mammalian protein synthesis eukaryotic initiation factor 4B with the poly(A)-binding protein by caspase- and viral protease-mediated cleavages.

Differential requirements for caspase-8 activity in the mechanism of phosphorylation of eIF2alpha, cleavage of eIF4GI and signaling events associated with the inhibition of protein synthesis in apoptotic Jurkat T cells.

The role of 5'-leader length, secondary structure and PABP concentration on cap and poly(A) tail function during translation in Xenopus oocytes.

Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cells.

The non-canonical CDK2 activator SPY1 uses separable mechanisms to activate phosphorylated and unphosphorylated CDK2.

Bisecting GlcNAc in N-glycan regulates synaptic maturation.

Loss of O-GlcNAc Transferase activity impairs the dynamic formation of protective stress granules in ischemic cardiomyocytes.

De novo flavonoid production in engineered Escherichia coli.

Atypical p38 kinase signaling and pathological impact on human health.

Solution Structures of Glycosaminoglycan-bound CXCL8 Complexes Determined by Small-Angle X-Ray Scattering (SAXS).

Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles.

Expression, Purification, and Structural Characterization of Membrane Proteins: A Case Study of the ABC Transporter MsbA.

A Dynamic Boolean Model of the Mammalian Cell Cycle: Enhanced Robustness and Mutational Analysis.

Electrical Properties in Biological Materials.

Conformational Ensemble and Stabilization of Insulin by a Choline Ionic Liquid Elucidated through Markov State Models.

Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory.

Related Experiment Videos

Initiation of protein synthesis in mammalian cells

Related Concept Videos

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