Michler's Ketone: β-Cyclodextrin Host-Guest Inclusion Complex for Enhancing the Ultraviolet Protection Factor of...

Area of Science:

• Materials Science
• Photochemistry
• Textile Chemistry

Background:

• Michler's ketone (MK) is a potential UVR absorber.
• Cotton fabrics require enhanced UV protection for various applications.

Purpose of the Study:

• To evaluate the UVR filtering ability of MK on cotton fabric.
• To investigate the enhancement of UV protection by forming an inclusion complex of MK with beta-cyclodextrin (β-CD).

Main Methods:

• Formation and characterization of MK:β-CD inclusion complex.
• Spectral analysis and molecular docking to understand the complex structure.
• Testing UV filtering efficiency and calculating Ultraviolet Protection Factor (UPF) on cotton fabric.

Main Results:

• The MK:β-CD complex demonstrated significantly enhanced UVR filtering compared to MK alone.
• Molecular docking revealed vertical insertion of MK into the β-CD cavity, with the -C=O group at the center.
• Cotton fabric treated with the MK:β-CD complex achieved a UPF of 46.

Conclusions:

• The MK:β-CD inclusion complex provides superior UV protection on cotton fabric.
• The inflexible fit of MK within the β-CD cavity enhances UVR dissipation.
• MK:β-CD complex is a promising candidate for developing effective sun protective textiles.