Related Experiment Video
Updated: Aug 18, 2026

Colony Forming Cell (CFC) Assay for Human Hematopoietic Cells
Published on: December 18, 2010
Abstract:
The assay for CFU-GEMM has provided a measurement for pluripotent hemopoietic precursors in normal and abnormal hemopoiesis. While these cells are able to express the functional repertoire that includes not only myelopoiesis but also lymphopoiesis attempts to determine their self-renewal have shown little or no self-renewal capability. It is currently not known whether this observation reflects culture conditions favouring differentiation processes and suppressing self-renewal, or whether the observation made in culture truly reflects the potential of cells in vivo. Recent advances in molecular biology have lead to the identification of the genomic sequences of at least one of the hemopoietic growth factors thus confirming their importance as regulators.
More Related Videos
Related Concept Videos
Hematopoiesis
Differentiation of Common Myeloid Progenitor Cells
Regulation of Hematopoietic Stem Cells
Overview of Hematopoiesis
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...
Production of Formed Elements
Most HSCs commit to...
Role of Hematopoietic Growth Factors
Thrombopoietin (TPO), mainly released by the liver,...

