Related Experiment Video
Updated: Sep 29, 2025

08:31
Three-dimensional Optical-resolution Photoacoustic Microscopy
Published on: May 3, 2011
18.4K
Silicon-photonics acoustic detector for optoacoustic micro-tomography
Yoav Hazan1, Ahiad Levi1, Michael Nagli1
1Technion - Israel Institute of Technology, Haifa, 3200003, Israel.
Nature Communications
|March 19, 2022
Summary
Researchers developed a miniaturized acoustic detector for high-resolution optoacoustic tomography. This novel detector achieves sub-20µm resolution, overcoming limitations of current medical imaging technologies.
Area of Science:
- Biomedical Engineering
- Medical Imaging
- Photonics
Background:
- Current medical ultrasound and optoacoustic (photoacoustic) imaging use beam-forming and tomography, limited by piezoelectric transducer miniaturization for resolutions beyond 100 µm.
- High-resolution imaging often relies on microscopy, but bulky apparatus and long acquisition times hinder clinical use.
Purpose of the Study:
- To demonstrate a miniaturized acoustic detector for high-resolution tomographic imaging.
- To overcome the resolution and practicality limitations of existing medical acoustic imaging techniques.
Main Methods:
- Developed a miniaturized acoustic detector using an optical resonator on a silicon-photonics platform.
- Coated the resonator with a sensitivity-enhancing elastomer to improve acoustic signal detection and eliminate surface acoustic wave interference.
- Achieved imaging with spread functions below 20 µm.
Main Results:
- Demonstrated a novel acoustic detector capable of tomographic imaging with sub-20 µm resolution.
- Successfully applied the detector in vivo for high-resolution optoacoustic tomography.
- The device overcomes the miniaturization efficiency issues of piezoelectric transducers.
Conclusions:
- The miniaturized optical resonator-based acoustic detector enables unprecedented resolution in optoacoustic tomography.
- This technology offers a promising alternative for high-resolution, clinically applicable medical imaging.
- The approach addresses key limitations in current ultrasound and photoacoustic imaging systems.

