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Post-discharge persistent headache and smell or taste dysfunction after hospitalisation for COVID-19: a single-centre

Tuba Akıncı1

  • 1Department of Neurology, University of Health Sciences, Haydarpaşa Numune Training and Research Hospital, Selimiye, Tıbbiye Cd No:23, 34668 Üsküdar, Istanbul, Turkey. tubaags@yahoo.com.

Irish Journal of Medical Science
|March 19, 2022
PubMed

Insights

Persistent headaches after hospitalization for coronavirus disease-19 (COVID-19) were linked to ongoing smell and taste dysfunction. This suggests a common cause for these lingering symptoms in COVID-19 survivors.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Otolaryngology

Background:

  • Headache is a common symptom in patients hospitalized with coronavirus disease-19 (COVID-19).
  • The persistence of headache and its relationship with other COVID-19 related symptoms require further investigation.

Purpose of the Study:

  • To assess the frequency, characteristics, and duration of headaches in hospitalized COVID-19 patients.
  • To explore the association between persistent headaches and smell/taste dysfunction post-discharge.

Main Methods:

  • A prospective study evaluated 85 hospitalized COVID-19 patients with headaches.
  • Neurological assessments were conducted, and patients were followed up via phone 3 months post-discharge to track symptom persistence.

Main Results:

  • 20% of patients experienced persistent headaches 3 months after discharge.
  • 65.3% reported smell/taste dysfunction, with 25.9% experiencing it long-term.
  • Persistent headaches were significantly associated with persistent smell/taste dysfunction (59% vs 6%, p<0.001).

Conclusions:

  • A correlation exists between persistent headaches and persistent smell/taste dysfunction in COVID-19 patients.
  • This association may indicate shared underlying pathophysiological mechanisms.
  • Further research is warranted to elucidate the mechanisms behind these persistent neurological and sensory symptoms.
Abstract

Keywords:
COVID-19HeadacheHypogeusia/ageusiaHyposmia/anosmia

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