Related Experiment Video
Updated: Sep 29, 2025

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
Published on: December 20, 2024
Association Between Systemic Corticosteroid Use and Mortality in Patients with Epiglottitis
Yuya Kimura1, Taisuke Jo2,3, Norihiko Inoue4,5
1Clinical Research Center, National Hospital Organization Tokyo National Hospital, 3-1-1 Takeoka, Tokyo, Japan.
Systemic corticosteroids may improve outcomes for patients with epiglottitis requiring airway management. This treatment was associated with reduced 30-day mortality and lower medical costs in a large cohort study.
Area of Science:
- Emergency Medicine
- Critical Care
- Pharmacology
Background:
- Epiglottitis is a serious condition requiring airway management.
- The role of systemic corticosteroids in epiglottitis treatment remains unclear.
Purpose of the Study:
- To investigate the association between systemic corticosteroid treatment and outcomes in patients with epiglottitis requiring airway management.
Main Methods:
- Retrospective cohort study using a nationwide inpatient database (2010-2019).
- Compared patients receiving systemic corticosteroids (methylprednisolone ≥40 mg/d) within 2 days of admission to those not receiving corticosteroids.
- Used inverse probability of treatment weighting (IPTW) for analysis.
Main Results:
- Corticosteroid treatment was linked to significantly lower 30-day in-hospital mortality (0.9% vs. 3.1%).
- Patients receiving corticosteroids had lower total medical costs.
- No significant difference was observed in 7-day mortality or length of hospital stay.
Conclusions:
- Systemic corticosteroids may offer benefits for epiglottitis patients needing airway management.
- Further research could solidify the role of corticosteroids in managing epiglottitis.
More Related Videos
05:18Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
Published on: May 26, 2023
04:56In Vitro Method to Control Concentrations of Halogenated Gases in Cultured Alveolar Epithelial Cells
Published on: October 23, 2018
Related Concept Videos
COPD: Management Using Bronchodilators and Corticosteroids
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes: