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Updated: Sep 29, 2025
Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization
Published on: September 2, 2022
Development of dendrimer-like glucan-stabilized Pickering emulsions incorporated with β-carotene
Yaning Shi1, Fan Ye2, Yingjie Zhu3
1College of Food Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, PR China.
Abstract:
The impact of sugary maize dendrimer-like glucan octenyl succinate (OSA-SMDG) on the storage stability and antioxidant activity of β-carotene (BC)-loaded emulsions as well as bioaccessibility were investigated. The encapsulation efficiency of β-carotene in emulsions containing 3% OSA-SMDG (3OSA-SMDG-BC) or 5% OSA-SMDG (5OSA-SMDG-BC) was 89.6% and 94.9%, respectively. The antioxidant activity of both emulsions was higher than that of pure β-carotene. During simulated digestion, the particle size of emulsions was immediately reduced, whereas zeta-potential was continuously increased in intestinal digestion. After 2 h digestion, the free fatty acids (FFA) release rate of 3OSA-SMDG-BC and 5OSA-SMDG-BC was significantly higher than that of blank emulsion. Bioaccessibility of β-carotene encapsulated in 3OSA-SMDG-BC and 5OSA-SMDG-BC was also significantly higher than that of blank emulsion. FFA release rate and β-carotene bioaccessibility of 5OSA-SMDG-BC were higher than that of 3OSA-SMDG-BC. These results demonstrated that OSA-SMDG could be used to fabricate food-grade O/W Pickering emulsion as a delivery system for bioactive compounds.
