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Updated: Sep 29, 2025

Techniques to Induce and Quantify Cellular Senescence
Published on: May 1, 2017
The Biological Process of Aging and the Impact of Ionizing Radiation
Mohammed Al-Jumayli1, Stephen L Brown2, Indrin J Chetty2
1Senior Adult Oncology Program, Moffitt Cancer Canter, Tampa, FL.
Abstract:
Ionizing radiation is used to create models of accelerated aging because the processes of aging and radiation injury share common elements. In this chapter we review the biological processes of aging and the similarities and impact of ionizing radiation on those processes. The information draws on data from laboratory studies and from epidemiology studies of radiation exposure victims. The chapter reviews the effects of radiation on DNA, cells, and organs systems on aged adults. The science of aging and the effect of radiation on the aging process are areas of active research and our understanding is evolving.
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