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Global Research Status of Multiple Organ Dysfunction Syndrome During 2001-2021: A 20-Year Bibliometric Analysis
Peng-Yue Zhao1,2, Yun Xia3, Zheng-Bo Tao4
1Department of General Surgery, First Medical Center of Chinese PLA General Hospital, Beijing, China.
Background:
Multiple Organ Dysfunction Syndrome (MODS) is a major cause of high morbidity and mortality among patients in intensive care units (ICU). Although numerous basic and clinical researches on MODS have been conducted, there is still a long way to go to prevent patients from entering this stage. To our knowledge, no bibliometric analyses of MODS have been reported, this study, therefore, was conducted to reveal MODS research status and trends during 2001-2021.
Methods:
All relevant literature covering MODS during 2001-2021 were extracted from Web of Science. An online analysis platform of literature metrology was used to analyze the publication trends. VOSviewer software was used to collect and analyze the keywords and research hotspots related to MODS.
Results:
As of July 31, 2021, a total of 994 MODS-related articles from 2001 to 2021 were identified. The United States accounted for the largest number of publications (31.1%), followed by China and Germany, with 186 and 75 publications, respectively. Among all the institutions, the University of Pittsburgh published the most papers related to MODS (21). Critical Care Medicine published the most papers in this field (106). Professor Moore EE, who had the most citation frequency (1847), made great achievements in MODS research. Moreover, analysis of the keywords identified three MODS research hotspot clusters: "mechanism-related research," "clinical research," and "diagnostic research."
Conclusions:
The United States maintained a top position worldwide and made the most outstanding contribution in the MODS field. In terms of publication, China was next only to the United States, but there was a disproportion between the quantity of publications and citation frequency. The institution University of Pittsburgh and journal Critical Care Medicine represent the highest level of research in this field. During the 20 years from 2001 to 2021, basic MODS research has been in-depth yet progressed relatively slowly recently, but the outbreak of COVID-19 has to some extent set off an upsurge of clinical research in MODS field.
Insights
This bibliometric analysis reveals trends in Multiple Organ Dysfunction Syndrome (MODS) research from 2001-2021. The United States leads publications, with key research clusters in mechanisms, clinical aspects, and diagnostics.
Area of Science:
- Critical care medicine
- Pathophysiology
- Bibliometrics
Background:
- Multiple Organ Dysfunction Syndrome (MODS) is a significant cause of mortality in intensive care units (ICUs).
- Despite extensive research, effective prevention strategies for MODS remain elusive.
- This study provides the first bibliometric analysis of MODS research.
Purpose of the Study:
- To analyze the research status and trends of Multiple Organ Dysfunction Syndrome (MODS) globally.
- To identify key research hotspots and influential institutions and publications in the MODS field.
- To understand the evolution of MODS research over a 20-year period (2001-2021).
Main Methods:
- A comprehensive literature search was conducted on Web of Science for articles published between 2001 and 2021.
- Bibliometric analysis was performed using an online literature metrology platform.
- VOSviewer software was utilized for keyword analysis and visualization of research hotspots.
Main Results:
- A total of 994 MODS-related articles were published between 2001 and 2021.
- The United States led in publications (31.1%), followed by China and Germany.
- Key research clusters identified were 'mechanism-related research,' 'clinical research,' and 'diagnostic research.'
Conclusions:
- The United States is the leading contributor to MODS research, with the University of Pittsburgh and Critical Care Medicine being highly influential.
- China shows a high publication volume but lower citation impact.
- Recent clinical research in MODS has surged, partly due to the COVID-19 pandemic.
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