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Updated: Sep 29, 2025

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Community-Acquired, Post-COVID-19, Methicillin-Resistant Staphylococcus aureus Pneumonia and Empyema
Cameron McCraw1, Sierra Forbush2, Kovid Trivedi3
1Pulmonology and Critical Care, Western University of Health Sciences, Lebanon, USA.
Secondary Staphylococcus aureus pneumonia, including MRSA, can occur after COVID-19 recovery. Early detection and treatment of these opportunistic infections are crucial for hospitalized patients.
Area of Science:
- Infectious Diseases
- Pulmonology
- Critical Care Medicine
Background:
- The COVID-19 pandemic has led to increased secondary infections, particularly nosocomial ones.
- Bacterial pneumonia is a significant complication in hospitalized COVID-19 patients.
- Multidrug-resistant organisms pose a growing threat in healthcare settings.
Observation:
- A 77-year-old male presented with multifocal pneumonia and right-sided empyema four weeks after initial COVID-19 diagnosis.
- The infection was caused by methicillin-resistant Staphylococcus aureus (MRSA).
- The patient required chest tube thoracostomy, intrapleural fibrinolysis, and eventually video-assisted thoracoscopy with decortication.
Findings:
- This case represents a rare instance of community-acquired MRSA lung infection post-COVID-19 recovery.
- MRSA empyema following COVID-19 pneumonia necessitates aggressive management.
- Successful treatment involved a combination of surgical intervention and targeted antibiotics.
Implications:
- Highlights the importance of vigilant monitoring for secondary infections in COVID-19 patients.
- Underscores the potential severity and diverse manifestations of opportunistic infections post-COVID-19.
- Emphasizes the need for comprehensive strategies to combat multidrug-resistant organisms in the context of viral pandemics.
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