Related Experiment Video
Updated: Sep 29, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Skin Metastasis Occurring 30 Years After Thyroidectomy for Papillary Thyroid Carcinoma
Mohammed S Alwhaid1, Olaa Mhish2, Mutahir A Tunio3
1Radation Oncology, King Faisal Specialist Hospital & Research Centre, Riyadh, SAU.
Abstract:
The skin is an extremely rare site of metastasis from papillary thyroid carcinoma (PTC) and is linked to underlying disseminated malignancy, which reflects a dismal prognosis. We present the case of a 70-years-old Saudi female who presented at our clinic with an eight-month history of two painful and itchy skin nodules over the scalp and the medial aspect of the right arm. She had a history of total thyroidectomy for PTC 30 years prior. Computed tomography-positron emission tomography showed multiple fluorodeoxyglucose avid lung and skeletal metastases. This case highlights the fact that skin nodules in a patient with a history of PTC should be assessed carefully with a high suspicion of skin metastasis to avoid any delay in treatment.

