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Slow-DEET-Release Mosquito-Repellent System Based on Poly(butylene succinate).

Hande Ece Yener1, Rafael Erdmann2, Katalee Jariyavidyanont1

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Biodegradable poly(butylene succinate) (PBS) strands were created with mosquito repellent N,N-diethyl-3-methylbenzamide (DEET). These strands show extremely slow DEET release, suggesting potential as long-lasting biodegradable repellent devices.

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Area of Science:

  • Polymer Science
  • Materials Science
  • Entomology

Background:

  • Mosquito-borne diseases necessitate effective and sustainable repellent solutions.
  • Biodegradable polymers offer environmentally friendly alternatives for controlled release applications.
  • N,N-diethyl-3-methylbenzamide (DEET) is a widely used and effective insect repellent.

Purpose of the Study:

  • To develop and characterize biodegradable poly(butylene succinate) (PBS) strands containing DEET.
  • To evaluate the evaporation characteristics of DEET from PBS matrices.
  • To assess the potential of these strands as slow-release repellent-delivery devices.

Main Methods:

  • Extrusion of bio-sourced and biodegradable PBS with varying DEET concentrations (up to 40 m%).
  • Microstructural analysis to observe DEET entrapment within the PBS superstructure.
  • Thermogravimetric analysis (TGA) at temperatures ranging from 60-100 °C to quantify DEET release.
  • Estimation of evaporation rates and time constants at lower service temperatures.

Main Results:

  • DEET was successfully incorporated into PBS strands via extrusion.
  • At DEET concentrations up to 20 m%, DEET was entrapped within the semicrystalline spherulitic superstructure of PBS.
  • At higher DEET concentrations (>20 m%), DEET partially segregated, forming its own macrophase.
  • Thermogravimetric analysis indicated an extremely low DEET release rate, with an estimated time constant of 1-2 years at 25 °C, irrespective of initial DEET concentration.

Conclusions:

  • Biodegradable PBS strands can effectively encapsulate DEET for controlled release applications.
  • The developed materials exhibit exceptionally slow evaporation rates, suggesting long-term efficacy.
  • These DEET-loaded PBS strands hold promise as sustainable, slow-release mosquito repellent devices.