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Risk Factors and Consequences of Lower Extremity Fracture Nonunions in Veterans With Spinal Cord Injury
Bridget Sinnott1, Cara Ray2, Frances Weaver2,3
1Charlie Norwood Veterans Affairs Medical Center Augusta GA USA.
Older veterans with long-term spinal cord injuries and disorders (SCID) who fracture their distal femur face a high risk of nonunion. These nonunions lead to severe complications like pressure injuries, osteomyelitis, and amputation, necessitating targeted interventions.
Area of Science:
- Orthopedics
- Traumatology
- Rehabilitation Medicine
Background:
- Lower extremity fractures are a significant concern in veterans with spinal cord injuries and disorders (SCID).
- Fracture nonunion can lead to substantial morbidity and impact functional outcomes.
- Identifying risk factors and consequences is crucial for improving patient care.
Purpose of the Study:
- To determine risk factors for lower extremity fracture nonunion in veterans with SCID.
- To identify the consequences and complications associated with these nonunions.
- To define a high-risk population for targeted interventions.
Main Methods:
- Utilized Veterans Health Administration (VHA) national administrative data from fiscal years 2005-2014.
- Identified a cohort of veterans with SCID and lower extremity fractures.
- Employed multivariable-adjusted logistic regression to compute odds ratios (OR) for fracture nonunion.
Main Results:
- Older age (OR=2.29), longer duration of SCID (OR=1.02), and distal femur fracture site were significant risk factors for nonunion.
- Fracture nonunions resulted in serious complications: pressure injuries (upwards of 1/3), osteomyelitis (13%), and subsequent amputation (almost 25%).
- A high-risk population identified: older veterans with long-duration SCID sustaining distal femur fractures.
Conclusions:
- Older veterans with SCID and distal femur fractures are at high risk for fracture nonunion.
- Nonunions in this population lead to severe complications, including amputation.
- Early identification and targeted interventions for signs of delayed union in high-risk individuals are recommended.
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