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Updated: Sep 29, 2025

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
Published on: May 16, 2025
Traditional Chinese Medicine Alleviates Ulcerative Colitis via Modulating Gut Microbiota
Wan Feng1, Lei Zhu1, Hong Shen1
1Department of Gastroenterology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Abstract:
Ulcerative colitis (UC) is a chronic inflammatory bowel disorder characterized by relapsing and remitting inflammation of the bowel. In recent decades, traditional Chinese medicine (TCM) has been widely used in the therapy of UC. However, its underlying mechanisms have not been sufficiently elucidated. Accumulating studies indicate that the gut microbial dysbiosis is closely related to UC. It has been demonstrated that TCM could alter the composition of intestinal microbiota by enriching beneficial and SCFA-producing bacteria and reducing pathogenic bacteria. In this review, we discussed recent evidence regarding the TCM and its role in modulating gut microbiota for the treatment of UC.
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