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Multiple myeloma with esophageal involvement: A rare case
Misako Tohata1, Yorimasa Yamamoto1, Hiroshi Harada2
1Department of Internal Medicine Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
DEN Open
|March 21, 2022
Summary
This case study reports the first instance of esophageal involvement in extramedullary multiple myeloma. The rare gastrointestinal lesion was discovered during endoscopy in a patient with symptomatic myeloma.
Area of Science:
- Oncology
- Gastroenterology
- Hematology
Background:
- Multiple myeloma is a plasma cell malignancy.
- Extramedullary disease, while known, is uncommon in the gastrointestinal tract.
Observation:
- A 77-year-old male presented with spinal cord compression and anemia.
- Diagnostic workup revealed symptomatic multiple myeloma.
- Anemia progression prompted upper endoscopy, revealing an esophageal lesion.
Findings:
- The esophageal lesion was diagnosed as extramedullary multiple myeloma.
- This represents the first reported case of esophageal involvement in multiple myeloma.
- The patient received radiation therapy, chemotherapy, and surgical resection.
Implications:
- Highlights the potential for rare extramedullary manifestations of multiple myeloma.
- Underscores the importance of thorough investigation for gastrointestinal lesions in myeloma patients.
- Contributes to the understanding of myeloma's diverse clinical presentations.
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