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Updated: Sep 29, 2025

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
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Published on: May 10, 2019

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Autophagy-Mediated Synaptic Refinement and Auditory Neural Pruning Contribute to Ribbon Synaptic Maturity in the

Rui Guo1, Yice Xu2, Wei Xiong1

  • 1Department of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Frontiers in Molecular Neuroscience
|March 21, 2022
PubMed
Summary

Auditory development involves significant changes in cochlear ribbon synapses. Autophagy activity plays a key role in refining these synapses and pruning spiral ganglion nerve (SGN) fibers during early hearing maturation.

Keywords:
auditory developmentautophagycochlear ribbon synapsesneural fibers pruningsynaptic refinement

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