Postviral Gastroparesis Associated With SARS-CoV-2 Infection in a Pediatric Patient

Area of Science:

• Pediatric Gastroenterology
• Infectious Diseases
• Viral Pathogenesis

Background:

• Postviral gastroparesis is a known complication following various viral infections.
• The gastrointestinal effects of SARS-CoV-2 infection are increasingly recognized, but postviral gastroparesis has not been previously associated with this virus.

Observation:

• A case report details a teenager presenting with symptoms of gastroparesis, including abdominal pain, early satiety, and vomiting.
• The patient had a likely asymptomatic SARS-CoV-2 infection approximately two months prior to symptom onset.
• Epidemiologic links, antibody testing, and clinical progression supported the hypothesis of a SARS-CoV-2 link.

Findings:

• The teenager's symptoms and significantly reduced gastric emptying were hypothesized to be secondary to postviral gastroparesis caused by SARS-CoV-2.
• Treatment involved supportive care and prokinetic agents.

Implications:

• This case suggests SARS-CoV-2 infection may be an additional cause of postviral gastroparesis in adolescents.
• Further research is warranted to understand the prevalence and mechanisms of SARS-CoV-2-induced gastroparesis.
• Early recognition and management may improve patient outcomes for this potential complication.