Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phase Transitions: Vaporization and Condensation02:39

Phase Transitions: Vaporization and Condensation

19.1K
The physical form of a substance changes on changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. Vaporization occurs when the thermal motion of the molecules overcome the intermolecular forces, and the molecules (at the surface) escape into the gaseous state. When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase...
19.1K
Distillation: Vapor–Liquid Equilibria01:01

Distillation: Vapor–Liquid Equilibria

3.0K
Distillation is a separation technique that takes advantage of the boiling point properties of disparate elements in a mixture. To perform distillation, we begin by heating a miscible mixture of two liquids with a significant difference in boiling points (at least 20°C). As the solution heats up and reaches the bubble point of the more volatile component, some molecules of the more volatile component transition into the gas phase and travel upward into the condenser, which is a glass tube...
3.0K
Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model01:09

Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model

487
Various dissolution theories provide insight into the factors that influence the dissolution rate. Danckwerts' Model suggests that turbulence, rather than a stagnant layer, characterizes the dissolution medium at the solid-liquid interface. In this model, the agitated solvent contains macroscopic packets that move to the interface via eddy currents, facilitating the absorption and delivery of the drug to the bulk solution. The regular replenishment of solvent packets maintains the...
487

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A model of 3D confluent tissue behaves as an under-constrained glass.

Soft matter·2026
Same author

Shape-transitions of a morphing illusory contour can be decoded during multiple-object tracking from the ongoing EEG.

Communications psychology·2026
Same author

Epithelial-mesenchymal interface guides cell shapes and axis elongation in embryonic explants.

Development (Cambridge, England)·2025
Same author

Curvature gradient drives polarized tissue flow in the <i>Drosophila</i> embryo.

Proceedings of the National Academy of Sciences of the United States of America·2023
Same author

Stiffening of under-constrained spring networks under isotropic strain.

Soft matter·2022
Same author

Anisotropy links cell shapes to tissue flow during convergent extension.

Proceedings of the National Academy of Sciences of the United States of America·2020
Same journal

Rheology of <i>Escherichia coli</i> suspensions with various bacterial morphologies and motion characteristics.

Soft matter·2026
Same journal

Stress-boundary-memory feedback drives vortical-polar transitions in softly confined active matter.

Soft matter·2026
Same journal

CAGE ionic liquids meet biomembranes: unraveling molecular mechanisms and partitioning kinetics.

Soft matter·2026
Same journal

Steady and oscillatory propulsion in reactive swimming droplets.

Soft matter·2026
Same journal

Axial forces in capillary liquid bridges of polymer solutions.

Soft matter·2026
Same journal

Dual-mode pH-programmable enzymatic hydrogel system for on-demand glucose generation.

Soft matter·2026
See all related articles

Related Experiment Video

Updated: Sep 29, 2025

Production of Membrane-Filtered Phase-Shift Decafluorobutane Nanodroplets from Preformed Microbubbles
07:10

Production of Membrane-Filtered Phase-Shift Decafluorobutane Nanodroplets from Preformed Microbubbles

Published on: March 23, 2021

2.8K

Phase separation dynamics in deformable droplets.

Simon Gsell1,2, Matthias Merkel1

  • 1Aix Marseille Univ, Université de Toulon, CNRS, CPT (UMR 7332), Turing Centre for Living Systems, Marseille, France. simon.gsell@univ-amu.fr.

Soft Matter
|March 21, 2022
PubMed
Summary
This summary is machine-generated.

Phase separation in stem cell aggregates, modeled as fluid droplets, reveals new routes to tissue organization. Advection and interface tension drive unique droplet shapes and patterns, mimicking early embryonic development.

More Related Videos

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure
08:02

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure

Published on: April 17, 2018

10.6K
Synthesis and Characterization of Multi-Modal Phase-Change Porphyrin Droplets
07:59

Synthesis and Characterization of Multi-Modal Phase-Change Porphyrin Droplets

Published on: October 15, 2021

3.8K

Related Experiment Videos

Last Updated: Sep 29, 2025

Production of Membrane-Filtered Phase-Shift Decafluorobutane Nanodroplets from Preformed Microbubbles
07:10

Production of Membrane-Filtered Phase-Shift Decafluorobutane Nanodroplets from Preformed Microbubbles

Published on: March 23, 2021

2.8K
Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure
08:02

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure

Published on: April 17, 2018

10.6K
Synthesis and Characterization of Multi-Modal Phase-Change Porphyrin Droplets
07:59

Synthesis and Characterization of Multi-Modal Phase-Change Porphyrin Droplets

Published on: October 15, 2021

3.8K

Area of Science:

  • Biophysics
  • Soft Matter Physics
  • Developmental Biology

Background:

  • Phase separation is crucial for spatial organization in biological systems, including embryonic development and stem cell aggregates.
  • Stem cell aggregates can mimic early embryonic axis formation through polar organization.
  • Modeling these aggregates as deformable two-phase fluid droplets offers insights into their behavior.

Purpose of the Study:

  • To numerically explore out-of-equilibrium routes to polar organization in deformable two-phase fluid droplets.
  • To investigate the interplay between spinodal decomposition and advection driven by interface tensions.
  • To characterize the influence of Peclet number (Pe) on phase separation dynamics.

Main Methods:

  • Hybrid finite-volume Lattice-Boltzmann simulations were employed.
  • The study focused on deformable two-phase fluid droplets suspended in a third fluid phase.
  • Analysis involved characterizing the Peclet number (Pe) to understand advection effects.

Main Results:

  • For high Peclet numbers (Pe), phase separation coarsening is accelerated.
  • Intermediate Pe leads to long-lived, elongated "croissant" droplets with alternating stripe patterns.
  • Surface tension asymmetry induces transient, rotationally symmetric states and Marangoni-like flows.

Conclusions:

  • Advection plays a critical role in phase separation within finite, deformable systems.
  • The study demonstrates how fluid dynamics and phase separation can lead to complex structures mimicking biological organization.
  • "Croissant" states represent near-equilibrium structures that coarsen slowly via Ostwald ripening-like processes.