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Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
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How have COVID-19 stringency measures changed scholarly activity?

Kim M Caudwell1, Alessandro Soranzo2, Lee Wei Lim3

  • 1College of Health & Human Sciences, Charles Darwin University, Darwin, Northern Territory, Australia.

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|March 21, 2022
PubMed
Summary
This summary is machine-generated.

Government restrictions during the COVID-19 pandemic reduced non-COVID-19 clinical trial registrations. Higher pandemic restrictions correlated with a greater drop in clinical trial activity, impacting future treatment discovery.

Keywords:
COVID-19global burden of diseasegovernment restrictionsresearch productivityscientists

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Area of Science:

  • Public Health
  • Clinical Research
  • Epidemiology

Background:

  • The COVID-19 pandemic prompted widespread government restrictions on public movement.
  • These restrictions significantly impacted various sectors, including scientific research and clinical trials.

Purpose of the Study:

  • To investigate the impact of COVID-19 government restrictions on non-COVID-19 clinical trial registrations.
  • To quantify the relationship between the stringency of pandemic-related government measures and the decline in clinical trial activity.

Main Methods:

  • Analysis of registered non-COVID-19 clinical trials during the pandemic.
  • Utilizing the Oxford COVID-19 Government Response Tracker Stringency Index (SI) to measure restriction levels.
  • Correlating SI scores with the reduction in clinical trial registrations across different countries.

Main Results:

  • A notable decrease in the number of registered non-COVID-19 clinical trials was observed during the pandemic.
  • Countries with higher Stringency Index scores experienced a more pronounced reduction in clinical trial registrations.
  • The findings indicate a direct correlation between the severity of government-imposed restrictions and the decline in clinical trial activity.

Conclusions:

  • Government restrictions implemented during the COVID-19 pandemic have negatively affected the progress of non-COVID-19 clinical research.
  • The observed decline in clinical trial registrations poses a potential threat to the development of new treatments for various diseases.
  • Addressing the impact on clinical research is crucial for mitigating the long-term global health consequences.