Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Burn therapy 1985: acute management.

R G Tompkins, J F Burke

    Intensive Care Medicine
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Effective burn wound management requires early excision of dead tissue and wound closure, often using artificial skin for extensive injuries. Intensive nutritional support and bacterial controlled nursing units (BCNU) are crucial for survival, preventing infection and malnutrition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Methods for implantation of micro-wire bundles and optimization of single/multi-unit recordings from human mesial temporal lobe.

    Journal of neural engineering·2014
    Same author

    Mature religious behavior: A psychological perspective and its implications.

    Journal of religion and health·2013
    Same author

    Effect of insurance status on postacute care among working age stroke survivors.

    Neurology·2012
    Same author

    Enrollment of women and minorities in NINDS trials.

    Neurology·2011
    Same author

    Ultrastructural studies on the lymphatic anchoring filaments.

    The Journal of cell biology·2009
    Same author

    Ultrastructural studies on the lymphatic anchoring filaments.

    The Journal of cell biology·2009
    Same journal

    Publisher Correction: Current knowledge and challenges of sepsis-associated encephalopathy.

    Intensive care medicine·2026
    Same journal

    Prehospital airway and ventilatory management: a collaborative and narrative review.

    Intensive care medicine·2026
    Same journal

    Rapid coma with bilateral basal ganglia involvement.

    Intensive care medicine·2026
    Same journal

    From size to function: moving beyond body mass index to frailty and central adiposity phenotypes.

    Intensive care medicine·2026
    Same journal

    Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial.

    Intensive care medicine·2026
    Same journal

    Hypercalcemia in intensive care unit: pathophysiological mechanisms and clinical implications.

    Intensive care medicine·2026
    See all related articles

    Area of Science:

    • Burn Injury Management
    • Infectious Disease Control
    • Wound Healing

    Background:

    • Mortality from burn injuries is primarily due to infection, complicated by metabolic disturbances, malnutrition, and reduced host resistance.
    • Traditional burn therapies (antibiotics, topical treatments, debridement) are insufficient for large wounds and associated nutritional deficits.
    • Devitalized tissue and depressed immunity create a high risk for virulent secondary infections in burn patients.

    Purpose of the Study:

    • To outline a rational approach to managing severe burn injuries.
    • To emphasize the importance of early surgical intervention and wound closure.
    • To highlight the role of nutritional support and infection control in improving outcomes.

    Main Methods:

    • Early operative removal (excision) of devitalized burned tissue.

    Related Experiment Videos

  • Immediate wound closure using autografts or artificial skin for extensive burns.
  • Implementation of bacterial controlled nursing units (BCNU) for infection prevention.
  • Intensive nutritional support to meet caloric and protein needs.

    • Main Results:

    • Early excision and closure reduce the risk of infection and improve wound healing.
    • Artificial skin provides a viable option for immediate closure in massive burn injuries where autograft is insufficient.
    • BCNU significantly protects against cross-infection with virulent organisms.
    • Adequate nutritional support mitigates the catabolic response and negative nitrogen balance.

    Conclusions:

    • A paradigm shift towards early surgical debridement and closure, supplemented by artificial skin, antibiotics, and topical treatments, is essential for severe burns.
    • Maintaining host resistance through intensive nutritional support and preventing cross-contamination via BCNU are critical for survival.
    • This integrated approach addresses the multifaceted challenges of severe burn injury, including infection, malnutrition, and wound management.