Related Experiment Video
Updated: Sep 29, 2025

08:33
Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
Published on: June 25, 2019
8.4K
Sensitive skin: A relevant syndrome, be aware.
A Wollenberg1, A Giménez-Arnau2
1Department of Dermatology and Allergy, University Hospital, Ludwig Maximilian University, Munich, Germany.
Summary
Sensitive skin involves unpleasant sensations like stinging and burning, often triggered by cosmetics. Identifying these triggers is crucial for managing this common skin condition.
Area of Science:
- Dermatology
- Cosmetology
- Consumer Health
Background:
- Sensitive skin is characterized by heightened sensory perceptions such as stinging, burning, and itching, often without visible signs of disease.
- It is recognized as a syndrome by the International Forum for the Study of Itch (IFSI), significantly impacting quality of life.
- The condition is frequently triggered or exacerbated by environmental factors and cosmetic products.
Purpose of the Study:
- To define sensitive skin and its clinical manifestations.
- To identify common triggers, particularly cosmetic ingredients, that provoke sensitive skin symptoms.
- To highlight the need for developing improved skincare products for sensitive skin management.
Main Methods:
- Clinical definition and characterization of sensitive skin symptoms.
- Review of patient reports and common triggers, with a focus on cosmetic products.
- Analysis of the role of irritant substances in cosmetic formulations.
Main Results:
- Sensitive skin is defined by abnormal sensory perceptions in response to normally innocuous stimuli.
- Cosmetics are frequently reported as the primary trigger for sensitive skin symptoms.
- The prevalence of sensitive skin is increasing with global cosmetic use.
Conclusions:
- Sensitive skin is a prevalent condition requiring identification of specific triggers.
- Cosmetic formulations containing potentially irritant substances are key factors in symptom exacerbation.
- There is a significant need for research and development of safe and effective skincare products for sensitive skin.
Related Concept Videos
Skin Diseases and Disorders
4.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.4K
Sensory Functions of the Skin
6.1K
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
6.1K
Hypersensitivities
1.2K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
1.2K
Reticular Dermis
3.3K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
3.3K
Allergic Reactions
29.0K
Overview
29.0K
Changes in Skin Color: Clinical Perspectives
2.5K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.5K

