Frequency of Prescribing and Administering Premedication in Paediatric Surgical Patients at a Tertiary Care Hospital:

Ausaf A Khan1, Durriya Raza1, Muhammad Qamar-Ul-Hoda1

  • 1Anaesthesiology, Aga Khan University Hospital, Karachi, PAK.

Cureus
|March 23, 2022
PubMed

Insights

Many pediatric surgical patients did not receive preoperative premedication. When prescribed, details like drug route and timing were often missing, impacting stress and infection management.

Area of Science:

  • Anesthesiology
  • Pediatric Surgery
  • Pharmacology

Background:

  • Preoperative stress in pediatric surgical patients can lead to negative outcomes like behavioral issues and infections.
  • Multimodal approaches, including ward-based pharmacological premedication, are recommended to mitigate preoperative stress.
  • This study assessed the prescription and administration rates of premedication in pediatric surgical patients.

Purpose of the Study:

  • To determine the frequency of premedication prescription for pediatric surgical patients.
  • To evaluate the completeness of premedication orders, including drug, dose, route, and timing.
  • To assess the administration and documentation of premedication in the inpatient ward.

Main Methods:

  • Retrospective observational study of 125 pediatric patients (1-16 years) undergoing elective surgery.
  • Review of preoperative forms and medical records from October to December 2014.
  • Data collection focused on premedication orders and administration timing in wards.

Main Results:

  • Premedication was not prescribed to 40% of pediatric patients.
  • For prescribed premedications, drug and dose were usually specified (98.7%), but route (26.6%) and timing (12%) were often omitted.
  • Ward nurses administered premedication in 89.3% of prescribed cases, with documentation in 95.5%, though timing was frequently missing (46.3%).

Conclusions:

  • A significant proportion of pediatric surgical patients did not receive prescribed preoperative premedication.
  • Incomplete prescription details (route, timing) were common when premedication was ordered for ward administration.
  • Gaps in prescription and documentation highlight areas for improvement in pediatric preoperative care.
Abstract

Related Concept Videos

Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.4K
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
45
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
875
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.0K
Standard Precaution01:26

Standard Precaution

Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
2.3K
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response01:15

Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response

Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
145