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Updated: Sep 29, 2025

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
Published on: March 2, 2020
A selective fluorescence turn-on sensing coordination polymer for antibiotic aztreonam
Xiaomei Wang1, Cheng Liu1, Ming Wang1
1Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing University of Posts & Telecommunications, Nanjing 210023, China. iamxhzhou@njupt.edu.cn.
Abstract:
Reports about the detection of antibiotic aztreonam (ATM) are very rare. Herein, a fluorescent "turn-on" sensing coordination polymer 1 for ATM is described. The good linear relationship between the luminescence intensity and ATM concentration (0-0.135 mM) gave the slope of 20 380 M-1 and detection limit of 4.44 × 10-7 M. This work is of great significance, not only because 1 is a sensing material for ATM with excellent selectivity, sensitivity, anti-interference ability and recoverability, but also because it expands the catalogue of antibiotics detection.
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