Related Experiment Video
Updated: Aug 5, 2026

Membrane Potential Dye Imaging of Ventromedial Hypothalamus Neurons From Adult Mice to Study Glucose Sensing
Published on: November 28, 2013
Periventricular hypothalamic cells in the rat brain contain insulin mRNA
Abstract:
In situ hybridization histochemistry with a 35S-labeled oligodeoxyribonucleotide probe for insulin was performed in the rat. Labeled cells were observed in the pancreas and in the periventricular nucleus of the hypothalamus. No labeling was seen elsewhere in the brain, including the olfactory bulb, the choroid plexus, and the tissue adjacent to the lateral ventricles. This finding suggests that insulin may be released from cells in the periventricular nucleus for transport via cerebrospinal fluid to other brain regions.
More Related Videos
Related Concept Videos
Insulin Secretory Vesicles
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are co-secreted in...
Insulin: The Receptor and Signaling Pathways

