Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diffusion01:12

Diffusion

205.3K
Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
205.3K
Passive Diffusion: Overview and Kinetics01:17

Passive Diffusion: Overview and Kinetics

854
Passive diffusion is a critical process that allows small lipophilic drugs to cross the cell membrane along a concentration gradient. This mechanism's efficiency depends on four primary factors: the membrane's surface area, the drug's lipid-water partition coefficient, the concentration gradient, and the membrane's thickness.
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting...
854
Behavior of Gas Molecules: Molecular Diffusion, Mean Free Path, and Effusion03:48

Behavior of Gas Molecules: Molecular Diffusion, Mean Free Path, and Effusion

29.7K
Although gaseous molecules travel at tremendous speeds (hundreds of meters per second), they collide with other gaseous molecules and travel in many different directions before reaching the desired target. At room temperature, a gaseous molecule will experience billions of collisions per second. The mean free path is the average distance a molecule travels between collisions. The mean free path increases with decreasing pressure; in general, the mean free path for a gaseous molecule will be...
29.7K
External and Internal Respiration01:24

External and Internal Respiration

5.1K
External respiration occurs in the lungs, and it is the first step in the journey of oxygen inside the body. When we inhale, oxygen enters our lungs and diffuses across the thin alveolar membrane. The alveoli are tiny, air-filled sacs that provide a vast surface area for gas exchange. Oxygen in the alveoli has a higher partial pressure (105 mmHg) than in the adjacent pulmonary capillaries (40 mmHg), establishing a pressure gradient. As a result, oxygen molecules move from the alveoli into the...
5.1K
Protein Diffusion in the Membrane01:24

Protein Diffusion in the Membrane

4.7K
Proteins show rotational as well as lateral diffusion across the membrane. The lateral diffusion of proteins was confirmed through the cell fusion experiment where mouse and human cells were fused, resulting in hybrid cells. When the human and mouse cells fused, the specific membrane proteins on human and mouse cells were marked with the red and green-fluorescent markers, respectively. Initially, the red and green fluorescence was located on the respective hemisphere of the cell. As time...
4.7K
Drug Absorption Mechanism: Passive Membrane Transport01:23

Drug Absorption Mechanism: Passive Membrane Transport

5.3K
Passive transport is a method of drug absorption where small, lipid-soluble drugs can move across the cell membrane. This movement happens along the concentration gradient, which is a natural flow from higher to lower concentration areas. The speed at which the drug moves is directly related to its lipid–water partition coefficient. This means that the more a drug dissolves in lipids, the faster it diffuses or spreads throughout the body. It is important to note that most drugs are either...
5.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermochemical Micro-Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Hydrophobic Promoter-Enhanced Tandem Catalysis for Alkene Epoxidation With H<sub>2</sub> and O<sub>2</sub>.

Angewandte Chemie (International ed. in English)·2026
Same author

Study on the effects and molecular mechanisms of arsenic-induced kidney damage in mice.

Ecotoxicology and environmental safety·2026
Same author

Conjugation-induced π-electron modulation in pyridazine-integrated covalent organic frameworks for SO<sub>2</sub> capture and upcycling.

Nature communications·2026
Same author

Confinement-Driven Anomalous Behaviors for Diffusion in Zeolites: Mechanisms and Beyond.

Accounts of chemical research·2026
Same author

Characterization of high-purity <i>Aeromonas salmonicida</i> extracellular vesicles and their inhibitory activity against <i>Pseudomonas fluorescens</i> biofilm formation.

Food science and biotechnology·2026

Related Experiment Video

Updated: Sep 29, 2025

Synthesis of Zeolites Using the ADOR Assembly-Disassembly-Organization-Reassembly Route
08:26

Synthesis of Zeolites Using the ADOR Assembly-Disassembly-Organization-Reassembly Route

Published on: April 3, 2016

13.4K

Diffusive Skin Effect in Zeolites.

Wei Rao1,2, Jiamin Yuan2,3, Xiaomin Tang2

  • 1School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 15000, P.R. China.

The Journal of Physical Chemistry Letters
|March 23, 2022
PubMed
Summary

Molecules in zeolites migrate along pore walls, a "diffusive skin effect." This phenomenon enhances reactant contact with active sites, boosting zeolite catalyst performance.

More Related Videos

Adsorption Device Based on a Langatate Crystal Microbalance for High Temperature High Pressure Gas Adsorption in Zeolite H-ZSM-5
09:46

Adsorption Device Based on a Langatate Crystal Microbalance for High Temperature High Pressure Gas Adsorption in Zeolite H-ZSM-5

Published on: August 25, 2016

11.8K
Nanostructured Ag-zeolite Composites as Luminescence-based Humidity Sensors
07:13

Nanostructured Ag-zeolite Composites as Luminescence-based Humidity Sensors

Published on: November 15, 2016

10.3K

Related Experiment Videos

Last Updated: Sep 29, 2025

Synthesis of Zeolites Using the ADOR Assembly-Disassembly-Organization-Reassembly Route
08:26

Synthesis of Zeolites Using the ADOR Assembly-Disassembly-Organization-Reassembly Route

Published on: April 3, 2016

13.4K
Adsorption Device Based on a Langatate Crystal Microbalance for High Temperature High Pressure Gas Adsorption in Zeolite H-ZSM-5
09:46

Adsorption Device Based on a Langatate Crystal Microbalance for High Temperature High Pressure Gas Adsorption in Zeolite H-ZSM-5

Published on: August 25, 2016

11.8K
Nanostructured Ag-zeolite Composites as Luminescence-based Humidity Sensors
07:13

Nanostructured Ag-zeolite Composites as Luminescence-based Humidity Sensors

Published on: November 15, 2016

10.3K

Area of Science:

  • Heterogeneous catalysis
  • Materials science
  • Chemical engineering

Background:

  • Effective contact between reactants and active sites is crucial for heterogeneous catalysis.
  • Zeolites are widely used catalysts, but their catalytic mechanisms under confinement are not fully understood.

Purpose of the Study:

  • To investigate molecular diffusion in zeolites.
  • To understand the impact of molecular diffusion on zeolite-catalyzed reactions.

Main Methods:

  • Computational investigation of molecular diffusion in over 200 types of zeolites.
  • Analysis of guest-host interactions and diffusion barriers within zeolite pores.

Main Results:

  • Observation of a "diffusive skin effect" where molecules migrate along zeolite pore walls.
  • Demonstration that this effect enhances reactant-active site contacts and collisions.
  • Correlation between the diffusive skin effect and improved zeolite catalytic performance.

Conclusions:

  • The "diffusive skin effect" is a key factor in zeolite catalysis.
  • This finding provides fundamental insights into zeolite catalytic mechanisms under confinement.
  • Understanding this effect can lead to the design of more efficient zeolite catalysts.