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Updated: Sep 29, 2025

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
Published on: June 25, 2019
[Subacute parkinsonism as first symptom of primary CNS lymphoma]
Christian Hede Kirkedal1, Thor Høyer2, Peter Brøgger Christensen1
1Neurologisk Afdeling, Aalborg Universitetshospital.
Abstract:
Secondary parkinsonism due to cerebral neoplasia is a rare condition. We present a case report of a 73-year-old woman with three weeks of progressing right-sided parkinsonism. Cerebral MRI arouse suspicion of left-sided primary CNS-lymphoma in the left basal ganglia. Cerebralspinal fluid analyzed with flow cytometry revealed diffuse B-cell lymphoma. The patient was transferred to the department of haematology and was treated by standard primary CNS-lymphoma protocol. Five-month clinical control revealed marked recovery. At nine-month control an MRI of cerebrum showed almost complete regression of tumour.
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